nah no need, but i understand many people use marquis reagent for a rough appraisal.
im kind interested in why they feel the transporters are sufficient, and for only SERT, DAT and NET.
after all there are many classes of drugs that work on, NMDA receptors, GABA channels, or the Opioid receptors, or Canabinoid recepts (dimers). yeah what about the recently understood fact that many receptors form dimers where two neurotransmitter systems interact via a coupled arrangement of receptors.
what about PDE inhibitors? like caffeine, (also an adenosine antagonist). There are some stimulants that works via this pathway.
there there are the direct agonists, im pretty sure LSD for example is thought to act by direct action on various 5HT receptors rather than on the transporters. still if theyve got a completely automated system that can assay an unknown substance on human cells, (wonder what kind of cell they are), it sounds interesting. are we talking a completely automated patch clamp assay? or would a technician do the pipette positioning.
they have a mass spectrometer on a bus? woah. i would have expected perhaps IR spectroscopy but MS, thats one expensive bus.
Source: http://rss.slashdot.org/~r/Slashdot/slashdotScience/~3/sQmgFU5SEf4/story01.htm
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